Avogadro

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John Dalton (1776 - 1844) was able to estimate relative atomic masses of various molecules, the smallest unit that a chemical can exist in without losing its identity. His values were soon improved by Amadeo Avogadro (1776 - 1856), in 1811. Avogadro made the very important proposal that the volume of a gas (strictly, of an ideal gas ) is proportional to the number of atoms or molecules that are present. Hence, the relative molecular mass of a gas can be calculated from the mass of a sample of known volume.
BUT neither Avogadro nor Dalton knew how many molecules there were in a given mass of a substance.
This is historically significant because it means that, although Hahnemann realised that there was a limit to the dilutions that could be used, he had no way of knowing what that limit was.( Source: [WWW]http://dcscience.net/?p=243 )
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